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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPHA8 All Species: 10
Human Site: Y584 Identified Species: 24.44
UniProt: P29322 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29322 NP_065387.1 1005 111003 Y584 S D E E K M H Y Q N G Q A P P
Chimpanzee Pan troglodytes P0C0K6 1020 110674 T628 K R R G T G Y T E Q L Q Q Y S
Rhesus Macaque Macaca mulatta XP_001101560 1005 110887 Y584 S D E E K M H Y Q N G Q A P P
Dog Lupus familis XP_544509 1216 132649 E811 A F Q D S D E E K M H Q G W R
Cat Felis silvestris
Mouse Mus musculus O09127 1004 110746 Y583 S D E E K M H Y Q N G Q A P P
Rat Rattus norvegicus P54759 998 111935 Q590 C G Y S K A D Q E G D E E L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510807 979 108960 M577 Q D P E E E K M H F H N G H I
Chicken Gallus gallus O42422 993 111348 Q585 C G Y S K A D Q E G D E E L Y
Frog Xenopus laevis Q91694 985 109711 E584 K A K Q E A D E E K H L N Q G
Zebra Danio Brachydanio rerio O13146 981 109636 E584 A K Q D P E E E K M Q F Q H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 99.3 73.8 N.A. 95.1 56.1 N.A. 57.3 56.9 56 56.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 60.8 99.5 75.4 N.A. 97.1 72.8 N.A. 73.3 73 71.3 70.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 6.6 N.A. 100 6.6 N.A. 13.3 6.6 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 33.3 N.A. 100 20 N.A. 20 20 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 0 0 0 30 0 0 0 0 0 0 30 0 0 % A
% Cys: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 40 0 20 0 10 30 0 0 0 20 0 0 0 0 % D
% Glu: 0 0 30 40 20 20 20 30 40 0 0 20 20 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % F
% Gly: 0 20 0 10 0 10 0 0 0 20 30 0 20 0 20 % G
% His: 0 0 0 0 0 0 30 0 10 0 30 0 0 20 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 20 10 10 0 50 0 10 0 20 10 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 10 0 20 0 % L
% Met: 0 0 0 0 0 30 0 10 0 20 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 30 0 10 10 0 0 % N
% Pro: 0 0 10 0 10 0 0 0 0 0 0 0 0 30 30 % P
% Gln: 10 0 20 10 0 0 0 20 30 10 10 50 20 10 0 % Q
% Arg: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 30 0 0 20 10 0 0 0 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 20 0 0 0 10 30 0 0 0 0 0 10 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _